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Get Younger Looking Skin with OneSkin’s Science-Backed Face Topical Supplement
BEAUTY

Get Younger Looking Skin with OneSkin’s Science-Backed Face Topical Supplement

Tracy Teel
Tracy T.

Jan 06, 2023

It’s formulated with “the only peptide that’s scientifically proven to reverse the skin’s biological age.”


OneSkin partnered with Beautytap’s diverse community of certified beauty professionals for trusted, detailed, unpaid reviews. We are sharing this post with you as part of this collaboration and to learn more about their brand. All opinions are our own. Thank you for your support.

What do you know about skinspan? How about longevity scientists? When it comes to skincare, we’d all like to believe that companies set out to ensure our skin’s long-term health and ability to actually improve visibly over time.

Sadly, that isn’t always the case. But the four co-founders of OneSkin – who hold doctoral degrees in immunology, skin regeneration and tissue engineering, bioinformatics with an emphasis in genomics, and molecular biology – created a cutting-edge line of skin health products that go right to the source of skin aging to prove that how you age is not inevitable.

An Unintended Mission

If you believe that some things are meant to be, and that some discoveries emerge when you aren’t actively pursuing them, then you won’t be surprised to learn that the founders of OneSkin never intended to create a skincare company.

While using their proprietary algorithm to determine how effective topical skincare is, they learned that many products increase skin aging instead of decreasing it. Today, their OS-01 FACE Topical Supplement proves that reversing aging is, indeed, possible with the right product.

“It's time for a radical shift in the way we care for our skin—one where we prioritize skin health and enjoy better-looking skin as a result.”

Skin wrinkle improvement after 12 weeks of OS-01 FACE Topical Supplement. Left: baseline; Right: 12 weeks of treatment. / Photo source: www.oneskin.co

Claims Validated by Science

What sets OneSkin apart from every product on the market is the company’s approach to testing its products on real human skin that has been replicated from human skin cell donors. By growing skin cells in the lab and closely observing how OS-01 improves the skin by eliminating damaged cells, OneSkin determined that their unique peptide:

  • Thickens the epidermal layer, minimizing fine lines and wrinkles
  • Improves barrier function, reducing redness and protecting skin
  • Supports skin’s natural production of hyaluronic acid, collagen, and elastin, keeping it hydrated, strong, and firm
  • Improves the look of age spots by hindering melanin production
  • Helps skin look younger and stay healthier

In addition to the lab results, OneSkin’s 12-week clinical study further validated their findings, particularly the testing comparing products with and without the OS-01 peptide.

Just look at the results …

  • Skin smoothness and overall appearance improved in 100% of users
  • Skin evenness, radiance, pores and firmness improved in 95.5% of users 
  • Skin elasticity improved in 90% of users
  • The appearance of wrinkles diminished in 87% of users 
  • Skin barrier improved by an average of 15%

Read more Oneskin expert reviews

Refreshingly Honest

Consumers have come to expect a certain amount of transparency regarding formulation, evaluation methods, and efficacy, but testing methods vary almost as much as ingredients. OneSkin performs penetration testing because visible changes primarily occur when core ingredients reach the deeper layers of the skin.

This test validates not only the specific ingredients but their concentration levels as well, specifically the OS-01 peptide – “the only peptide that’s scientifically proven to reverse the skin’s biological age.”

OS-01 FACE Topical Supplement

OS-01 FACE Topical Supplement

The OS-01 FACE Topical Supplement comes with an outer refillable container made of partially recycled material and a disposable 30-day insert filled with a lightweight, serum-like moisturizer that should be used twice daily.

When co-founder Alessandra Zonari, PhD said that skin could look “2.2 years younger within five days,” I was cautiously optimistic. But when she explained that it targets senescent cells (i.e. damaged cells that can disrupt the way skin heals and protects itself ) I was borderline giddy.

The thought of getting retinoid-style benefits without the associated (and omnipresent) irritation and peeling hooked me, so I ditched my Retin-A as well as my evening AHA/BHA products and began using OS-01 instead.

Within a week, my skin tone looked more even upon waking, and my skin texture felt refined. A month has passed since I began using the OS-01 FACE Topical Supplement, and my pores have remained clear despite completely eliminating all AHA/BHA products from my routine.

That’s no small feat since I live in the California desert where blowing silt has made battling blackheads a year-round task.

Consider It a “Supplement,” Not Just a Moisturizer

It’s tempting to think of OS-01 as just a moisturizer, but the active ingredients in this “supplement” are no joke. Consider this an active (like vitamin C or retinol) in your routine and dedicate to using it for 30 days, and you’ll quickly see that improved skin hydration is just one of many visible benefits from this radical and revolutionary approach to skin health and longevity.


Tracy Ann Teel is a full-time freelance writer and the owner of Finesse Writing and Editing LLC. She’s a tutorial writer for San Francisco Globe’s beauty platform, FierceLeague.com, covering everything from skin and hair care to makeup and nail art. She writes for skincare companies, dermatologists, and cosmetic surgeons, and proudly taught at her MFA alma mater, the University of California Irvine, as a member of their adjunct faculty in English. She’s been a textbook reviewer for Prentice Hall, been recognized three consecutive years in the Who’s Who Among America’s Teachers, and has written professionally for 30+ years. Her poetry chapbook Such Dust was published by Finishing Line Press, and her work has appeared in Alaska Quarterly Review, Rattle, Pearl, Kaleidoscope, and Lake Arrowhead Life.

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